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Most significantly, Both PDA and Pt shell exhibit absorption in the Near-Infrared-II (NIR-II) region, which not only endow PDA@Pt with superior photothermal conversion efficiency for effective photothermal therapy (PTT) but also substantially enhances the nanomedicines capacity for UA degradation, O 2 production and ROS scavenging enzymatic activities

Because semaglutide activates only the GLP-1 pathwaynot the GIP pathway that tirzepatide engagessome patients notice slightly less pronounced appetite reduction or require time for their body to fully respond to this simpler signaling mechanism

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